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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPX2
All Species:
6.97
Human Site:
S157
Identified Species:
15.33
UniProt:
Q9ULW0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULW0
NP_036244.2
747
85653
S157
I
I
D
E
I
L
P
S
K
K
M
K
V
S
N
Chimpanzee
Pan troglodytes
XP_001153533
746
85517
S156
I
I
D
E
I
L
P
S
K
K
M
K
V
S
N
Rhesus Macaque
Macaca mulatta
XP_001109645
746
85683
P156
V
I
I
D
E
I
L
P
S
K
K
M
K
V
S
Dog
Lupus familis
XP_850934
748
86144
K158
H
E
I
P
P
S
K
K
M
K
V
S
N
N
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_082385
745
85876
K159
A
T
D
C
P
P
Q
K
R
M
K
V
S
H
K
Rat
Rattus norvegicus
NP_001101260
744
85432
P157
A
P
T
T
D
Y
P
P
N
K
K
M
K
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516385
623
69684
R145
T
S
S
P
P
L
P
R
L
R
L
K
T
A
P
Chicken
Gallus gallus
NP_989768
739
85048
P149
A
T
K
E
E
A
P
P
L
K
K
M
K
I
S
Frog
Xenopus laevis
NP_001086751
715
81991
S151
S
S
H
H
G
T
T
S
P
K
P
K
A
Q
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798362
948
108486
T288
V
K
P
K
N
L
V
T
S
W
G
N
S
N
T
Poplar Tree
Populus trichocarpa
XP_002327911
811
91572
G179
L
Q
T
E
N
A
D
G
K
E
S
S
K
N
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97.5
90.3
N.A.
79.2
79.1
N.A.
40.1
57.5
53.8
N.A.
N.A.
N.A.
N.A.
N.A.
31.6
Protein Similarity:
100
99.3
98.6
93.9
N.A.
87.6
87.4
N.A.
53
72.5
70
N.A.
N.A.
N.A.
N.A.
N.A.
49.4
P-Site Identity:
100
100
13.3
6.6
N.A.
6.6
13.3
N.A.
20
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
40
20
N.A.
13.3
20
N.A.
40
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
20.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
0
0
0
0
19
0
0
0
0
0
0
10
10
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
28
10
10
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
37
19
0
0
0
0
10
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
10
0
0
10
0
0
0
0
% G
% His:
10
0
10
10
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
19
28
19
0
19
10
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
10
10
10
0
0
10
19
28
64
37
37
37
0
19
% K
% Leu:
10
0
0
0
0
37
10
0
19
0
10
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
10
10
19
28
0
0
0
% M
% Asn:
0
0
0
0
19
0
0
0
10
0
0
10
10
28
19
% N
% Pro:
0
10
10
19
28
10
46
28
10
0
10
0
0
0
10
% P
% Gln:
0
10
0
0
0
0
10
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
10
10
10
0
0
0
0
0
% R
% Ser:
10
19
10
0
0
10
0
28
19
0
10
19
19
19
28
% S
% Thr:
10
19
19
10
0
10
10
10
0
0
0
0
10
0
10
% T
% Val:
19
0
0
0
0
0
10
0
0
0
10
10
19
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _